[Medline]. [4] Because no one theory appears to apply to all people with TGA, some speculate that TGA may have multiple different causes. [2][30], If the condition lasts longer than 24 hours, it is not considered TGA by definition. Generally, TGA is a solitary event, however, patients can experience more than one event with very similar symptoms and recovery. Transient global amnesia (TGA) is a temporary and isolated disorder of memory. It's not a risk factor for stroke or epilepsy. [17][35], TGA is most common in people between age 56 and 75,[8] with the average age of a person experiencing TGA being approximately 62. Internal jugular vein valve incompetence and intracranial venous anatomy in transient global amnesia. September 1, 2020, NIH-Supported Research Survey to Examine Impact of COVID-19 on Rare Diseases Community Sudden onset of memory loss, verified by a witness, Retention of personal identity despite memory loss, Normal cognition, such as the ability to recognize and name familiar objects and follow simple directions, Absence of signs indicating damage to a particular area of the brain, such as limb paralysis, involuntary movement or impaired word recognition, Duration of no more than 24 hours and generally shorter, No evidence of seizures during the period of amnesia, Medical procedures, such as angiography or endoscopy, Acute emotional distress, as might be provoked by bad news, conflict or overwork. 2006. [9] These occasional recurrences usually involve no long-term morbidity or death. [31][32], The prognosis of "pure" TGA is very good. If you have problems viewing PDF files, download the latest version of Adobe Reader, For language access assistance, contact the NCATS Public Information Officer, Genetic and Rare Diseases Information Center (GARD) - PO Box 8126, Gaithersburg, MD 20898-8126 - Toll-free: 1-888-205-2311. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. The cause of TGA is unknown. Transient global amnesia (TGA) is a clinical syndrome with no clear etiology identified. Visit the group’s website or contact them to learn about the services they offer. For men, transient global amnesia occurs more often after a physical precipitating event. Transient global amnesia. UpToDate - Author Royalties. The period of memory loss varies and may extend back hours to days or weeks, but only in rare instances, years. [12] Verbal and cognitive impairments have been observed days after TGA attacks, of such severity that the researchers estimated the effects would be unlikely to resolve within a short time frame. TEA, as opposed to "pure" TGA, is also characterized by "two unusual forms of memory deficit …: (i) accelerated long-term forgetting (ALF): the excessively rapid loss of newly acquired memories over a period of days or weeks and (ii) remote autobiographical memory loss: a loss of memories for salient, personally experienced events of the past few decades."[5]. [Medline]. You may not remember information you are told, and you may repeat the same questions. Transient global amnesia: clinical characteristics and prognosis. Daroff RB, et al. Lauria G, Gentile M, Fassetta G, et al. Choi BS, Kim JH, Jung C, Kim SY. 76(3):438-41. Sudden onset of memory loss, verified by a witness 2. [Medline]. The main identifiable symptom of transient global amnesia is the sudden, but temporary, loss of short-term memory and not being able to form new memories. Transient global amnesia (TGA) is a sudden, temporary interruption of short-term memory. J Comput Assist Tomogr. 2003 Apr. [8] However, despite the fact that EEG readings are usually normal during a TGA attack, and other usual symptoms of epilepsy are not observed with TGA,[16] it has been speculated that some initial epileptic attacks present as TGA. TGA is een syndroom dat zich kenmerkt door een acuut optredend algeheel geheugenverlies. 106(4):1284-7, table of contents. 2009 Nov 19. New York: McGraw-Hill; 1997: 429-30. Based on data from Rochester, Minnesota, Miller et al determined an incidence of 5.2 cases per 100,000 population. Choose a doctor and schedule an appointment. [Medline]. Transient global amnesia associated with cardiac arrhythmia and digitalis intoxication. Ann Neurol. South Med J. [19], Cerebral ischemia is a frequently disputed possible cause, at least for some segment of the TGA population, and until the 1990s it was generally thought that TGA was a variant of transient ischemic attack (TIA) secondary to some form of cerebrovascular disease. 1986; 109:251-257. Attention is spared, visual-spatial skills are intact, and social skills are retained. Omega-3s to Prevent Alzheimer's: Who Benefits? He will also ask questions about your memory loss, and if you have any other symptoms. Lin KH, Chen YT, Fuh JL, Li SY, Chen TJ, Tang CH, et al. Transient global amnesia goes away on its own within 24 hours. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you log out, you will be required to enter your username and password the next time you visit. These resources provide more information about this condition or associated symptoms. Liang JF, Shen AL, Lin SK.
Neuro Endocrinol Lett. Carmel Armon, MD, MSc, MHS is a member of the following medical societies: American Academy of Neurology, American Academy of Sleep Medicine, American Association of Neuromuscular and Electrodiagnostic Medicine, American Clinical Neurophysiology Society, American College of Physicians, American Epilepsy Society, American Medical Association, American Neurological Association, American Stroke Association, Massachusetts Medical Society, Sigma XiDisclosure: Received research grant from: Neuronix Ltd, Yoqnea'm, Israel
Received income in an amount equal to or greater than $250 from: JNS - Associate Editor. [20][22][23][24][25], A history of migraine is a statistically significant risk factor identified in the medical literature. Arena JE, et al. Cejas C, Cisneros LF, Lagos R, Zuk C, Ameriso SF. Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug ReferenceDisclosure: Received salary from Medscape for employment. The condition most often affects people in middle or older age. Lauria G, Gentile M, Fassetta G, et al. 352(9125):397-9. Although the patients who presented with a TIA had a higher prevalence of vascular risk factors, those in the TGA group (who had DWI changes) were found to have significantly more carotid atherosclerosis. 1987 May. 2014 May. Management of acute stroke. Overall, the variety of findings on functional imaging studies may support the notion that TGA is a syndrome with not only a variety of precipitating causes but also of differing mechanisms. If you need reassurance, ask your doctor to go over the results of your neurological exam and diagnostic tests with you. Available for Android and iOS devices. rare disease research! Nakada T, Kwee IL, Fujii Y, Knight RT. "The most important part of management after diagnosis is looking after the psychological needs of the patient and his or her relatives. Try our interactive tool for help finding information, services, experts, financial aid, and more! Research suggests there also may be a link between patients who have a history of migraines and those who experience TGA. Immediate recall ability is preserved, as is remote memory; however, patients experience striking loss of memory for recent events and an impaired ability to retain new information. In most cases, there is no activity that triggers a transient global amnesia episode. A diagnostic investigation would then probably focus on some form of undetected ischemic attack or cranial bleed. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. Crossref Medline Google Scholar; 36 Posteraro L. Post-traumatic transient amnesia. Transient global amnesia isn't serious, but it can still be frightening. Transient global amnesia (TGA) is a clinical syndrome characterized by sudden-onset anterograde amnesia that typically lasts 4 to 6 hours but can last up to 24 hours.
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